Cannabis provides a variety of therapeutic effects, including pain relief, managing inflammation, IBS, and more, but one of its most well-known side effects is laughter therapy.

The type of cannabis strain you choose may lead to a more giggly high, namely sativa strains or hybrid strains with sativa dominance, because sativa gives you a more cerebral high and boosts your energy to keep the good times rolling.

Let’s dive deeper into why weed makes you laugh and which strains to look out for if you want the best toke tickles with your crew. 

Why Weed Makes You Laugh

Cannabinoids

THC, the main psychoactive component in cannabis, binds with the CB1 receptors in the brain, which leads to relaxation and lowered inhibitions, and it also amplifies emotions like happiness.

CBD is another key cannabinoid, but it’s less likely to give you the giggles. While it’s good for calming you down and boasts therapeutic effects like THC, you probably won’t start laughing at an inanimate object or your friend’s face like you would with a strain with THC in. 

Terpenes

Terpenes are the part of cannabis that provides the smell and flavor, and they have a role to play in getting the giggles, too.

Terpenes work alongside cannabinoids, affecting how you feel with the entourage effect. Depending on the type of terpene, your mood will get a boost, and the types of creative thoughts you have could go for a wild ride, too. 

Cannabis Type

The type of cannabis you choose will also make a difference in how much you laugh after consuming it. Indica strains provide a lot heavier highs, so while you may laugh uncontrollably, you may not have the energy to have a proper laugh sesh. On the other hand, Sativa uplifts and provides a social feel that is more conducive to laughter. 

Top Weed Strains Known for Their Laughter-Inducing Effects

Super Silver Haze

Green House Seeds in Amsterdam developed Super Silver Haze in the 90s, and it’s long been known as one of the most fun-filled cannabis strains around. This strain boosts energy and creativity thanks to the terpene profile or terpinolene for a slightly psychedelic feel, limonene for a mood boost, and pinene to keep you clear-headed throughout.

Laughing Buddha

As the name suggests, Laughing Buddha from Barney’s Farm will have you doubled over in laughter in no time, thanks to its euphoric and giggly vibes. The sativa-dominant setup is known to boost sociability and humor. If you’re heading to a comedy night or the movies, this strain will have you laughing in the aisles - don’t smoke it before a heavy drama or horror, or you may be asked to leave. 

Blue Dream

Look no further than DJ Short’s Blue Dream for a hybrid strain that enhances laughter. The man known as the “Willy Wonka of Pot” bred this hilarious strain that uplifts mood and gives users a euphoric experience. Terpenes like myrcene to balance your mood and limonene for a euphoric feeling make this strain check all the boxes for a good giggle.  

Pineapple Express

If you smoke weed, you’ll have seen Seth Rogen and James Franco getting further and further out of their depth in the hit stoner comedy Pineapple Express. After the movie became a hit, the strain began to gain popularity, too. For example, when you watch a film, you’ll laugh as soon as you take a hit of this strain. The tropical flavors are reminiscent of a cocktail on the beach, and the sativa-dominant combination of Trainwreck and Hawaiian keeps the party going. 

Sour Diesel

Sour Diesel is another household name houseplant responsible for cackles worldwide since it became a thing in the 90s. This high-energy strain makes everyday conversations with your pals seem like you’re talking to a top-class comedian, thanks to the cerebral high that sparks humor and creativity. Everybody at your gathering will want to take a hit when they whiff that recognizable scent and hear everybody else laughing.  

Green Crack

Green Crack always has people coming back for more. This energizing strain will heighten your mood and can lead to fits of laughter. Green Crack has long been a stalwart of parties from California to New York, with users highlighting some of the funniest nights of their lives after sharing a bong with their buds. 

Factors That Enhance Laughter-Inducing Effects

THC

THC plays a pivotal role in mood elevation and laughter. However, it's not the case that you laugh more if you keep cranking up the THC levels. The sweet spot is strains that hover around the 18-25% THC range, which provide a euphoric high but won't be overwhelming. 

Setting 

If you smoke a joint of one of our recommended strains and head to a job interview, you may not have your interviewer laughing hysterically like you. That's why picking the right setting and people to smoke with you is integral. Make sure you're comfortable, invite your best friends who know how to chill, and maybe bang on some tunes in the background to enhance the effects, too. 

Dosage

You don’t eat the rest of an edible before the first bite kicks in because you don’t want to plunge into a 10-hour hellscape of being too high. The same goes for puffing more than you should on a joint if you have a low tolerance. It’s tempting when the taste is fantastic, but take it slow and go at your own pace. Smoking more won’t always make you laugh more. 

Other Factors to Consider for a Perfect Laugh

The aforementioned entourage effect combines cannabinoids and terpenes in a particular strain and the outcomes they provide. It’s essential to choose a strain with a combination of cannabinoids and terpenes that give a laugh and complement each other well.

If you’ve had a good laugh on a strain before, stick to what you know, especially as you’ll already be ready for the effects, so you won’t be shocked when they kick in.

Try smoking and watching a comedy movie with your friends, or host your own comedy night where you all get to perform for your crew or try a craft together that you've never done. Even if the outcomes are bad, it’ll still be a funny experience. 

Conclusion

The best weed strains that make you laugh are sativa or sativa-dominant hybrids. Strains like Blue Dream, Pineapple Express, and Green Crack uplift your mood, enhance creativity, and boost laughter. If you want a laughter-filled experience, consume responsibly and try not to overdo it, or you could become a zombie on the couch instead. There are so many strains out there that you should experiment with your combinations to find the right one. 

FAQs

What is the most giggly strain of weed?

While this is up for debate, strains like Super Silver Haze and Laughing Buddha have been making people giggle since the early 90s. 

What chemical in weed makes you laugh?

THC and terpenes are responsible for making you laugh after consuming weed.